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Question

Is heterozygote advantage an example of stabilizing selection?


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Solution

Heterozygote

  1. When a diploid organism's cells have two distinct alleles of a gene—one wild-type allele and one mutant allele—they are said to be heterozygous at that gene locus.
  2. Heterozygosity refers to a certain genotype since the cell or organism is referred to as a heterozygote, especially for the offending allele.

Heterozygote advantage

  1. Yes, the stabilising selection is an example of heterozygote advantage.
  2. In a population, stabilising selection works against boundaries and in favour of intermediate aggregates.
  3. This typically makes reference to heterozygous benefits, in which a heterozygote is blessed by normal choice because it possesses advantages that homozygotes require.
  4. The circumstance where the heterozygous genotype has higher relative wellbeing than either the homozygous predominant or homozygous passive genotype is thus illustrated by the term “heterozygote advantage.”
  5. We refer to an allele as having a heterozygote advantage when a single copy of a disease allele does not cause disease but is beneficial to the person or organism that bears it.
  6. One such is sickle cell trait, which in heterozygotes protects against malaria but results in a fatal illness in homozygotes.
  7. Stabilizing selection favours the moderate aggregates while acting against both phenotypes.
  8. Because heterozygous people exhibit more bizarre phenotypes than either one or both homozygotes, the directional choice is addressed by heterozygote advantage in this study.
  9. The number of posterity, human birth weight, camouflage coat tone, and cactus spine density are some examples of what emerged via stabilising selection.

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