Question

Is sickle cell a missense mutation?

Answer 1

Sickle cell:

1. Sickle cell disease refers to a group of diseases in which the red blood cells distorts into sickle cells.
2. If both of the parents carry the sickle cell gene in their chromosomes then the offspring should have sickle cell disease.
3. Sickle cell disease is a missense mutation.
4. It is a type of point mutation wherein the beta-haemoglobin gene converts a GAG codon into a GUG codon.
5. Valine is produced here in the place of glutamic acid and it causes the disease.