Question

.............. is the best evidence for the lock and key theory of enzyme reaction.

• A. All isolated enzymes have been identified as proteins.
• B. Compounds similar in structure to substrate inhibit reactions.
• C. Enzymes are found in living organisms speed up certain reactions.
• D. Enzymes determine the direction of reaction.

Answer 1

The correct option is B Compounds similar in structure to substrate inhibit reactions.

Emil fischer proposed the Lock and key model for enzyme action in 1984. The theory stated that enzymes were structurally complementary to their substrates so that they fit together like a lock and key and forms an unstable intermediate enzyme substrate complex which further turns to product.