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Question
................ is the component that is responsible for the pathogenicity of bacteria causing Tuberculosis and Leprosy.
................ is the component that is responsible for the pathogenicity of bacteria causing Tuberculosis and Leprosy.
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Solution
The correct option is E Wax-D
Mycobacteria are rod shaped gram positive obligate aerobes. The bacterium is a facultative intracellular parasite of the macrophages. The cell wall complex contains peptidoglycan and almost 60% of the mycobacterial cell wall is a lipid. The lipid fraction of Mycobacterium tuberculosis and leprae cell wall consists of three major components, mycolic acids, cord factor, and wax-D. Mycolic acids prevent the phagosome-lysosome fusion when the bacteria are taken up by macrophages. Mycobacterial lipids have a major role in the pathogenicity of MTB.
Mycobacteria are rod shaped gram positive obligate aerobes. The bacterium is a facultative intracellular parasite of the macrophages. The cell wall complex contains peptidoglycan and almost 60% of the mycobacterial cell wall is a lipid. The lipid fraction of Mycobacterium tuberculosis and leprae cell wall consists of three major components, mycolic acids, cord factor, and wax-D. Mycolic acids prevent the phagosome-lysosome fusion when the bacteria are taken up by macrophages. Mycobacterial lipids have a major role in the pathogenicity of MTB.
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