Its said that lysosomes bursts when foreign particle is found in the cell and finishes it, somethimes when the whole cell is damaged, it engulf the whole cell also, then why in cases of cancer lysosomes dosent works?
Its said that lysosomes bursts when foreign particle is found in the cell and finishes it, somethimes when the whole cell is damaged, it engulf the whole cell also, then why in cases of cancer lysosomes dosent works?
Lysosomes don’t eat cancer cells for the same reason that they don’t eat normal cells: because their activity is highly regulated.
That said, you are on to something here, because some cancers have abnormal rates of lysosome activity (they seem to make a lot of junk that needs to be recycled, and may also use it to get rid of anti-cancer drugs), and if you *could* hyper-activate lysosomes only in cancer cells, it might be a good therapy.
In particular, lysosomes sometimes do eat their entire host cell, a process called autophagy, and there’s a lot of recent research on autophagy and cancer.
Lysosomes don’t eat cancer cells for the same reason that they don’t eat normal cells: because their activity is highly regulated.
That said, you are on to something here, because some cancers have abnormal rates of lysosome activity (they seem to make a lot of junk that needs to be recycled, and may also use it to get rid of anti-cancer drugs), and if you *could* hyper-activate lysosomes only in cancer cells, it might be a good therapy.
In particular, lysosomes sometimes do eat their entire host cell, a process called autophagy, and there’s a lot of recent research on autophagy and cancer.
