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Question

Juxtaglomerular apparatus is made up of

A
Juxtaglomerular cells, macula densa and lacis cells
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B
Juxtaglomerular cells, Purkinje cells and chief cells
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C
Juxtaglomerular cells, lacis cells and myoepithelial cells
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D
Juxtaglomerular cells, macula densa and argentaffin cells
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Solution

The correct option is A Juxtaglomerular cells, macula densa and lacis cells
Juxtaglomerular cells are the smooth muscle cells of both the afferent and efferent arterioles that are swollen and contain dark granules. These cells secrete renin. Macula densa is the epithelium of the distal convoluted tubule that come in contact with the afferent and efferent arterioles. These cells are denser than the other tubular cells. They act as chemoreceptors. Lacis cells are located in the interval between the macula densa and the afferent and efferent arterioles. The function of lacis cells is unknown. All these cells make up juxtaglomerular apparatus.
So the correct answer is 'Juxtaglomerular cells, macula densa and lacis cells'.

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