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Question

Juxtaglomerular cells secrete ____________(a) when there is fall in blood pressure (b) _________ ion concentration. Choose the correct option.

A
a-Renin, b-Chloride
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B
a-Carbonic anhydrase, b-Sodium
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C
a- ATPase, b-Potassium
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D
a-Renin, b-Sodium
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Solution

The correct option is B a-Renin, b-Sodium
Juxta-glomerular cells are specialized smooth muscle cells of the afferent arteriole, which supplies blood to the glomerulus. When the kidney receives the low volume of blood the juxtaglomerular cells are stimulated to release Renin.renin converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR. Angiotensin II also activates the adrenal cortex to release Aldosterone. Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR.
So, the correct answer is 'a-Renin, b-Sodium'.

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