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Question

Key and lock hypothesis of enzyme action was given by

A
Fischer
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B
Koshland
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C
Buchner
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D
Kuhne
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Solution

The correct option is A Fischer
Fischer gave the key and lock hypothesis in 1894. According to this, both enzymes and substrate molecules have specific geometrical shape. The active site of enzymes is rigid in its shape. There is no change in the active site before and after the reaction. It is similar to the system of lock and key. Thus, the correct option is A.

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