Klinefelters syndrome is characterised by a karyotype of
A
XYY
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B
XO
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C
XXX
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D
XXY
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Solution
The correct option is D XXY
Klinefelters syndrome occurs by the union of an abnormal XX egg
and a normal Y sperm or a normal X egg and abnormal XY sperm. The
individual has 2n = 41 chromosomes (44 + XXV). Such persons
are sterile males with undeveloped testes, mental retardation, sparse
body haii long limbs and with some female characteristics such as
enlarged breast Le. gynaecomastia. It is considered that more the X
chromosomes, greater is the mental defect. As the syndrome has two X
chromosomes, one Barr body is seen in this case.