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Question
Krebs cycle begins with which of the following reaction?
Krebs cycle begins with which of the following reaction?
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Solution
The correct option is C Oxaloacetate + Acetyl CoA
Krebs cycle is responsible for the complete metabolism of pyruvic acid in the mitochondria. The Krebs cycle begins with condensation of two carbon unit (acetyl-CoA) with a four-carbon unit (oxaloacetate) to form a six carbon atom containing organic acid (citric acid). The enzyme catalyzing this reaction is citrate synthase. As the first stable intermediate is citric acid, this cycle is also called as citric acid. The citric acid contains three carboxylic groups. Hence, the Krebs cycle is also called as the tricarboxylic acid cycle or TCA cycle.
Krebs cycle is responsible for the complete metabolism of pyruvic acid in the mitochondria. The Krebs cycle begins with condensation of two carbon unit (acetyl-CoA) with a four-carbon unit (oxaloacetate) to form a six carbon atom containing organic acid (citric acid). The enzyme catalyzing this reaction is citrate synthase. As the first stable intermediate is citric acid, this cycle is also called as citric acid. The citric acid contains three carboxylic groups. Hence, the Krebs cycle is also called as the tricarboxylic acid cycle or TCA cycle.
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