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B
Jacob and Monod in 1969
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C
Watson and Crick in 1953
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D
Watson and Crick in 1963
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Solution
The correct option is B Jacob and Monod in 1961
Jacob and Monod, 1961, proposed operon model to explain induction and suppression of enzyme synthesis based on their studies on inducible system for synthesis of β-galactosidase enzyme in E. coli. Watson and Crick worked on molecular structure of DNA, not on operon; which makes options C and D wrong.