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Question

Lactic acid is converted into glycogen most readily in

A
Muscles
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B
Liver
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C
Kidney
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D
Brain
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Solution

The correct option is B Liver
Instead of accumulating inside the muscle cells, lactate produced by anaerobic fermentation is taken up by the liver. This initiates the Cori cycle. In the liver, gluconeogenesis occurs, which reverses both glycolysis and fermentation by converting lactate first into pyruvate, and finally back to glucose. The glucose is then supplied to the muscles through the bloodstream. If muscle activity has stopped, the glucose is used to replenish the supplies of glycogen through glycogenesis.

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