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Question

Lampbrush chromosome found in the oocytes of amphibians is seen in ........ phase.

A
Leptotene
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B
Diplotene
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C
Pachytene
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D
None of the above
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Solution

The correct option is B Diplotene
Lampbrush Chromosomes (LBCs) are present in the oocytes of birds, lower vertebrata and invertebrates during the prolonged prophase of the first meiotic division. Oocyte development takes place during the meiotic prophase and for the majority of species ends in the metaphase of the first meiotic division. The major part of this development occurs in the diplotene. At that time, the diplotene chromosomes of certain groups of vertebrates, i.e., amphibians and birds, assume the form of lampbrush chromosomes (LBCs) and generate thousands of loops along their axes. The loops are transcriptionally active sites.

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