Question

Lathyrism due to consumption of kesari dal is characterised by

• A. Skeletal deformation and thinning of collagen fibres
• B. Skeletal abnormalities, diabetes mellitus and reproductive failure
• C. Retarded growth, precocious puberty and renal dysfunction
• D. Cardiovascular abnormalities, mental retardation and delayed puberty

Answer 1

Answer: (A)

Skeletal deformation and thinning of collagen fibres

Lathyrism is a disorder caused due to an excessive intake of the seeds of 𝘓𝘢𝘵𝘩𝘺𝘳𝘶𝘴 𝘴𝘢𝘵𝘪𝘷𝘶𝘴 (Kesari Dal) which affects the cross-linking of collagen causing thinning of collagen fibres.
Collagen is the major protein of connective tissues and a defect in their cross-linking leads to skeletal deformation.

Hence, option "Skeletal deformation and thinning of collagen fibres" is correct.

Diabetes mellitus, reproductive failure, precocious puberty, renal dysfunction, cardiovascular abnormalities, mental retardation and delayed puberty are not related to collagen thinning.