Dear student
changes often occur as a result of the combination of two different types of matter. There are certain rules that govern the combination of different elements to form compounds. These rules are known as Laws of chemical combination, which are:
1) Law of Conservation of Mass
2) Law of Constant Composition or Definite Proportions
3) Law of Multiple Proportions
4) Law of Reciprocal Proportion
5) Gay Lussac’s Law of Gaseous Volume
Only Law of Constant Composition or Definite Proportions have a limitation which is, It is not applicable if an element exists in different isotopes which may be involved in the formation of the compound. The elements may combine in the same ratio but the compounds formed may be different.
And one common limitaion is that these laws holds true provided all measurements of volumes are done under similar conditions of temperature and pressure.
Regards