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Question

Lesch Nyhan disease is an X-linked recessive disorder that causes neurlological damage in human beings. A survey of 500 males from caucasion population revealed that 20 were effected with this disorder. What is the frequency of the normal allele in this population?

A
9,6
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B
0.8
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C
0.096
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D
96
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Solution

The correct option is A 9,6

When a cross is made between a male and female with Lesch-Nyhan diseases in the next generation 1 or 2 male affected. In the 500 males, 20 were affected means, the frequency of a normal allele is 9, 6.

So, the correct option is ‘9,6’.

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