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Examples of Gene Therapy

Lesch Nyhan d...

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Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of 500 mates from a caucasion population revealed that 20 were effected with this disorder. What is the frequency of the normal allele in this population?

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Q. Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of 500 mates from a Caucasian population revealed that 20 were affected with this disorder.

What is the frequency of the normal allele in this population?

Q. Lesch Nyhan disease is an X-linked recessive disorder that causes neurological damage in human beings. A survey of

500

mates from a caucasion population revealed that

20

were effected with this disorder. What is the frequency of the normal allele in this population?

Q. Lesch Nyhan disease is an X-linked recessive disorder that causes neurlological damage in human beings. A survey of 500 males from caucasion population revealed that 20 were effected with this disorder. What is the frequency of the normal allele in this population?

Q. In a random mating population, frequency of disease causing recessive allele is 80%. What would be the frequency of carrier individual in population?

Q. In a population, the frequency of the dominant allele A is 0.6 and that of the recessive allele a is 0.4. What would be the frequency of the heterozygous genotype in a random mating population at equilibrium?

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