Liver cells have a particular organelle in adundance which contains enzymes that catalyse a series of reactions to detoxify both lipid soluble drugs and various harmful compounds produced by metabolism. Identify the cell organelle.
A
Rough endoplasmic reticulum
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B
Mitochondria
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C
Golgi Apparatus
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D
Smooth endoplasmic reticulum
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Solution
The correct option is B Smooth endoplasmic reticulum Smooth ER is abundant in the liver, where it contains enzymes that metabolise various lipid-soluble compounds. These detoxifying enzymes inactivate a number of potentially harmful drugs (e.g., phenobarbital) by converting them into water-soluble compounds that can be eliminated from the body in the urine. The smooth ER is thus involved in multiple aspects of the metabolism of lipids and lipid-soluble compounds.