Question

Major and minor grooves can be seen in

• A. Polypeptide
• B. RNA
• C. DNA
• D. Chromatin

Answer 1

The correct option is C DNA

DNA has the double helical structure where the two strands are tightly coiled over each other. B- DNA has right-handed helix with the major and minor groove. The diameter of the DNA is 20 A${}^o$. The number of base pairs in one turn is 10 and the distance between base pairs is 3.4 A${}^o$. At major grooves, the base pairs are far apart while at minor groove the base pairs are closer. Major grooves have base pairs at a distance the DNA binding protein can easily interact with the bases.

So, the correct answer is option A.