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Question

Match the class of compounds given in Column I with their functions given in Column II

ColumnIColumnII(i)Antagonists(a)Communicate message between two neurons and that between neurons to muscles(ii)Agonists(b)Bind to the receptor site and inhibit its natural function(iii)Chemical messenger(c)Crucial to body's communication process(iv)Inhibitors(d)Mimic the natural messenger(v)Receptors(e)inhibit activities of enzymes

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ColumnIColumnII(i)Antagonists(b)Bind to the receptor site and inhibit its natural function(ii)Agonists(d)Mimic the natural messenger(iii)Chemical messenger(a)Communicate message between two neurons and that between neurons to muscles(iv)Inhibitors(e)Inhibit activities of enzymes(v)Receptors(c)Crucial to body's communication process

(i) Antagonist

Antagonist drugs are used when blocking of messages is required. For example, Cimetidine which prevents histamine from attaching to the receptor side and secret HCl.

(i) Antagonists (b) Bind to the receptor site and inhibit its natural function

(i) Antagonists (b) Bind to the receptor site and inhibit its natural function



(ii) Agonist

Agonist drugs are useful when there is a lack of chemical messenger. So, it mimic the natural messenger.



(ii)AgonistsMimic the natural messenger

(iii) Chemical messenger

In the body, message between two neurons and that between neurons to muscles is communicated through certain chemicals. These chemicals, known as chemical messengers are received at the binding sites of receptor proteins.

(iii) Chemical messenger (a) Communicate message between two neurons and that between neurons to muscles

(iv) Inhibitors

It blocks the binding site of the enzyme and prevents the binding of the substrate or inhibits the catalytic activity of the enzyme.

(iv) Inhibitors (e) Inhibit activities of enzymes

(v) Receptors

Receptors are proteins that are crucial to the body's communication. They are embedded in the cell membrane in such a way that their small part possessing active site projects out of the surface of the membrane and opens on the outside region of the cell membrane.


(v) Receptors (c) Crucial to body's communication process


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