Question

Match the columns.

	I		II
$1$	Sickle cell anaemia	a	$7$th chromosome
$2$	Phenylketonuria	b	$4$th chromosome
$3$	Cystic fibrosis	c	$11$th chromosome
$4$	Huntington's disease	d	X chromosome
$5$	Colour blindness	e	$12$th chromosome

• A. $1$-a, $2$-c, $3$-d, $4$-b, $5$-e
• B. $1$-c, $2$-e, $3$-a, $4$-b, $5$-d
• C. $1$-b, $2$-c, $3$-d, $4$-e, $5$-a
• D. $1$-b, $2$-a, $3$-c, $4$-e, $5$-d
• E. $1$-d, $2$-e, $3$-c, $4$-b, $5$-a

Answer 1

The correct option is B $1$-c, $2$-e, $3$-a, $4$-b, $5$-d

• Sickle cell disease is caused by a mutation in the hemoglobin-Beta gene found on chromosome 11
• Phenylketonuria is an autosomal recessive disorder, caused by mutations in both alleles of the gene for phenylalanine hydroxylase (PAH), found on chromosome 12.
• Cystic fibrosis is an inherited disease caused by mutations (changes) in a gene on chromosome 7, one of the 23 pairs of chromosomes that children inherit from their parents.
• Huntington's disease is a progressive brain disorder caused by a single defective gene on chromosome 4
• Genes responsible for the most common, inherited color blindness are on the X chromosome.

So, the correct answer is '1-c, 2-e, 3-a, 4-b, 5-d'.