Question

Match the entries in Column I with those of Column II and choose the correct answer.

	Column - I		Column - II
(A)	Restriction endonucleases	(P)	Kohler and Milstein
(B)	Polymerase chain reaction	(Q)	Alec Jeffreys
(C)	DNA fingerprinting	(R)	Arber
(D)	Monoclonal antibodies	(S)	Karry Mullis

• A. $\left(A\right)-\left(R\right),\left(B\right)-\left(S\right),\left(C\right)-\left(Q\right),\left(D\right)-\left(P\right)$
• B. $\left(A\right)-\left(R\right),\left(B\right)-\left(Q\right),\left(C\right)-\left(S\right),\left(D\right)-\left(P\right)$
• C. $\left(A\right)-\left(Q\right),\left(B\right)-\left(R\right),\left(C\right)-\left(S\right),\left(D\right)-\left(P\right)$
• D. $\left(A\right)-\left(Q\right),\left(B\right)-\left(S\right),\left(C\right)-\left(R\right),\left(D\right)-\left(Q\right)$

Answer 1

Answer: (A)

$\left(A\right)-\left(R\right),\left(B\right)-\left(S\right),\left(C\right)-\left(Q\right),\left(D\right)-\left(P\right)$

Restriction enzymes are enzymes that cut a DNA molecule at a particular place. Its mode of action was first demonstrated by Werner Arber in 1906.

Polymerase chain reaction is used for amplification of DNA which was first demonstrated by Kary Mullis.

DNA fingerprinting is used to establish a link between biological evidence and a suspect in a criminal investigation. It was first developed by Alec Jeffreys.

Monoclonal antibodies are the specific antibodies produced by myeloma cells and spleen cells immunised by a specific antigen. It was first produced by Kohler and Milstein.

So, the correct answer is option A.