Question

Match the following :

A. VNTR	p. Largest gene
B. Introns and Exons	q. DNA fingerprinting
C. Dystrophin	r. Bulk DNA
D. Satellite DNA	s. Splicing

• A. A - q, B - s, C - p, D - r
• B. A - s, B - p, C - q, D - r
• C. A - r, B - s, C - p, D - q
• D. A - q, B - p, C - s, D - r

Answer 1

Answer: (A)

A - q, B - s, C - p, D - r

• Every strand of DNA has pieces that contain genetic information that informs an organism's development (exons) and pieces that, apparently, supply no relevant genetic information at all (introns).
• These sequences called variable number tandem repeats (VNTRs). Every human being has some VNTRs.
• To determine if a person has a particular VNTR, a Southern Blot is performed, and then the Southern Blot is probed, through a hybridization reaction, with a radioactive version of the VNTR in question.
• The pattern which results from this process is what is often referred to as a DNA fingerprint. So, A with q.
• Splicing is the process of editing the nascent precursor messenger RNA (pre-mRNA) transcript.
• After splicing, introns are removed and exons are joined together (ligated). So, B matches with s.
• Dystrophin is a rod-shaped cytoplasmic protein and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane and it is the largest gene.

• Satellite DNA consists of very large arrays of tandemly repeating, non-coding DNA and is basically the bulk DNA.
• Thus, the correct answer is an option (A),