Question

Match the following and select the correct option.

	Column I		Column II
(a)	Clostridium butylicum	(i)	Cyclosporin-A
(b)	Trichoderma polysporum	(ii)	Butyric acid
(c)	Monascus purpureus	(iii)	Citric acid
(d)	Aspergillus niger	(iv)	Blood cholesterol lowering agent

• A. (a)-(i), (b)-(ii), (c)-(iv), (d)-(iii)
• B. (a)-(iv), (b)-(iii), (c)-(ii), (d)-(i)
• C. (a)-(iii), (b)-(iv), (c)-(ii), (d)-(i)
• D. (a)-(ii), (b)-(i), (c)-(iv), (d)-(iii)

Answer 1

The correct option is D (a)-(ii), (b)-(i), (c)-(iv), (d)-(iii)

Microbes are widely utilised for industrial acid production. Some of the examples are as follows:-

• Clostridium butylicum is a bacterium utilised in the production of butyric acid.
• Aspergillus niger is a fungus used in the production of citric acid.

Following are some of the examples of bioactive molecules produced by microbes:-

• Trichoderma polysporum is the fungus that produces Cyclosporin-A. It is used as an immunosuppressive agent in patients who underwent organ-transplantation.
• The yeast, Monascus purpureus, produces statins which have been commercialised as blood-cholesterol lowering agents. The statins competitively inhibit the enzyme responsible for cholesterol synthesis.