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Question

Match the following and select the correct option.

Column I Column II
(a) Clostridium butylicum (i) Cyclosporin-A
(b) Trichoderma polysporum (ii) Butyric acid
(c) Monascus purpureus (iii) Citric acid
(d) Aspergillus niger (iv) Blood cholesterol lowering agent

A
(a)-(i), (b)-(ii), (c)-(iv), (d)-(iii)
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B
(a)-(iv), (b)-(iii), (c)-(ii), (d)-(i)
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C
(a)-(iii), (b)-(iv), (c)-(ii), (d)-(i)
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D
(a)-(ii), (b)-(i), (c)-(iv), (d)-(iii)
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Solution

The correct option is D (a)-(ii), (b)-(i), (c)-(iv), (d)-(iii)
Microbes are widely utilised for industrial acid production. Some of the examples are as follows:-
  • Clostridium butylicum is a bacterium utilised in the production of butyric acid.
  • Aspergillus niger is a fungus used in the production of citric acid.
Following are some of the examples of bioactive molecules produced by microbes:-
  • Trichoderma polysporum is the fungus that produces Cyclosporin-A. It is used as an immunosuppressive agent in patients who underwent organ-transplantation.
  • The yeast, Monascus purpureus, produces statins which have been commercialised as blood-cholesterol lowering agents. The statins competitively inhibit the enzyme responsible for cholesterol synthesis.

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