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Question

Match the following co-factors with their examples:

A
Catalase
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B
Zinc
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C
NADP
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Solution

Three kinds of co-factors are identified:
  • Prosthetic groups: They are organic compounds that are tightly bound to the apoenzyme. Examples: catalase and peroxidase.
  • Co-enzymes: They are also organic compounds but their association with apoenzyme is only transient. Examples: NAD and NADP.
  • Metal ions: They are inorganic metals which form coordinate bonds at the active site of the enzyme with the substrate. Example: zinc ion in the proteolytic enzyme carboxypeptidase.

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