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Question

Match the following list of bioactive substances and their roles:
Bio active SubstanceRole(i) Statin(a) Removal of oil stains(ii) Cyclosporin A(b) Removal of clots from blood vessels(iii) Streptokinase(c) Lowering of blood cholesterol(iv) Lipase(d) Immunosuppressive agent


A

i b, ii c, iii a, iv d

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B

i d, ii b, iii a, iv c

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C

i d, ii a, iii d, iv c

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D

i c, ii d, iii b, iv a

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Solution

The correct option is D

i c, ii d, iii b, iv a


Some compounds produced by microbes have therapeutic benefits that exceed their antibiotic applications. For example, statins are a class of compounds produced by fungi that inhibit the production of cholesterol. Another bioactive molecule called Cyclosporin A produced by the fungus Trichoderma polysporum, is used as an immunosuppressive agent in organ-transplant patients to ensure that the new organ is not rejected by the recipient and it integrated into the recipient’s body seamlessly. Streptokinase is a protein produced by the bacterium Streptococcus that enhances the action of a human protein that clears blood clots. Lipase is an enzyme that digests lipids. It is used for digesting oily stains on clothes. Some important lipase-producing bacterial genera include Bacillus, Pseudomonas and Burkholderia.

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