Match the human disorders shown in Group I with the biochemical processes in Group II. Choose the correct combination.
Group I Group II P. Phenylketonuria i. Melanin synthesis Q. Albinism ii. Conversion of phenylalanine to tyrosine R. Homocystinuria iii. Tyrosine degradation S. Argininemia iv. Methionine metabolism v. Urea Synthesis
Match the human disorders shown in Group I with the biochemical processes in Group II. Choose the correct combination.
| Group I | Group II |
| P. Phenylketonuria | i. Melanin synthesis |
| Q. Albinism | ii. Conversion of phenylalanine to tyrosine |
| R. Homocystinuria | iii. Tyrosine degradation |
| S. Argininemia | iv. Methionine metabolism |
| v. Urea Synthesis |
The correct option is A P-ii, Q-i, R-iv, S-v
Phenylketonuria - an autosomal recessive disorder causing absence of
hydroxylase enzyme thus there is an inability of conversion of phenylalanine to tyrosine causing phenyl pyruvic idiocy and
arthritis.
Albinism - an
autosomal recessive condition causing tyrosinase deficiency. So, the
melanin synthesis cannot take place.
Homocystinuria - a
disorder of methionine metabolism causing abnormal deposition of
homocysteine and its metabolites.
Argininimia -
Autosomal recessive disorder. Due to deficiency of arginase enzyme,
the arginine and ammonia get accumulated into the blood.
Thus matching all
the options we find that correct answer is 'P-ii,
Q-i, R-iv, S-v'.
Phenylketonuria - an autosomal recessive disorder causing absence of hydroxylase enzyme thus there is an inability of conversion of phenylalanine to tyrosine causing phenyl pyruvic idiocy and arthritis.
Albinism - an autosomal recessive condition causing tyrosinase deficiency. So, the melanin synthesis cannot take place.
Homocystinuria - a disorder of methionine metabolism causing abnormal deposition of homocysteine and its metabolites.
Argininimia - Autosomal recessive disorder. Due to deficiency of arginase enzyme, the arginine and ammonia get accumulated into the blood.
Thus matching all the options we find that correct answer is 'P-ii, Q-i, R-iv, S-v'.
