Question

Match the lists and find the correct option.

	I		II
a	Down's syndrome	I	$45$, X
b	Edward syndrome	II	$47$ XX $+18$
c	Klinefelter's syndrome	III	$47$ XX $+18$
d	Patau's syndrome	IV	$47$ XX$+21$
e	Turner's syndrome	V	$47$ XXY

• A. a-III, b-IV, c-II, d-I, e-V
• B. a-II, b-III, c-IV, d-V, e-I
• C. a-IV, b-III, c-V, d-II, e-I
• D. a-IV, b-II, c-V, d-III, e-I

Answer 1

The correct option is C a-IV, b-III, c-V, d-II, e-I

• Down syndrome is usually caused by an error in cell division called “nondisjunction.” Nondisjunction results in an embryo with three copies of chromosome 21 instead of the usual two.
• Edwards Syndrome (also known as Trisomy 18 (T18) or Trisomy E) is a genetic disorder caused by the presence of all or part of an extra 18th chromosome.
• Klinefelter syndrome (KS) also known as 47, XXY or XXY, is the set of symptoms that result from two or more X chromosomes in males.
• Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13
• Turner syndrome affects only females as the result of a missing or partially missing X chromosome.

So, the correct answer is 'a-IV, b-III, c-V, d-II, e-I'.