Question

Maturation of pro-insulin into insulin (simplified) is given below. Select the correct option:

• A. A-Proinsulin, B-A peptide, C-B peptide, D-Free C peptide
• B. A-A peptide, B-Proinsulin, C-B peptide, D-Free C peptide
• C. A-Proinsulin, B-B peptide, C-A peptide, D-Free C peptide
• D. None of the above

Answer 1

The correct option is B A-A peptide, B-Proinsulin, C-B peptide, D-Free C peptide

• Insulin used for diabetes was earlier extracted from the pancreas of the slaughtered cattle and pigs.
• Insulin consists of two short peptide chains: Chain A and Chain B, linked together by a disulfide bridge.

So, the correct option is 'A-A peptide, B-Pro-insulin, C- B peptide, D- Free C Peptide'.