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Insulin in Humans

Maturation of...

Question

Maturation of proinsulin into insulin takes place after

A

Joining of C – peptide

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B

Removal of C – peptide

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C

Removal of disulphide bridge

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D

Addiion of disulphide bridge

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Solution

The correct option is B
Removal of C – peptide

Pro insulin is the precursor of insulin which consists of ‘A’ chain bonded with ‘B’ chain by disulphide bridges and has free ‘C’ chain. Whereas mature insulin is free of ‘C’ peptide chain, so removal of ‘C’ peptide leads to Insulin.

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Similar questions

Q. With regard to insulin choose correct options.

(a) C-peptide is not present in mature insulin.
(b) The insulin produced by rDNA technology has C-peptide.
(c) The pro-insulin has C-peptide
(d) A-peptide and B-peptide of insulin are interconnected by disulphide bridges.

Choose the correct answer from the options given below

Q. Read the following statements carefully and select the correct option.
Statement I: Insulin is produced by alpha cells of islets of Langerhans.
Statement II: During maturation of insulin from proinsulin, C peptide is removed for proper folding.

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Insulin in Humans

Standard X Biology

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