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Question
Methylation of DNA commonly occurs in the sequence
Methylation of DNA commonly occurs in the sequence
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Solution
The correct option is A CmG
The cytosines (C) of DNA sometimes carry a methyl group (Cm). This has no effect on its coding properties, but the presence of methyl groups does affect the likelihood of a DNA sequence being transcribed. Typically, highly methylated genes are inactive, whereas active genes have low methylation levels. During development, methylation levels are changed, so the same gene may have different patterns of methylation (marks) in different tissues. These alternative patterns can be transmitted to daughter cells. They are transmitted because methylation occurs symmetrically, usually in CG doublets (or in plants in CNG triplets, where N can be any base) in which CmG on one strand is paired with GC"' on the other.
So, the correct answer is 'CmG'.
The cytosines (C) of DNA sometimes carry a methyl group (Cm). This has no effect on its coding properties, but the presence of methyl groups does affect the likelihood of a DNA sequence being transcribed. Typically, highly methylated genes are inactive, whereas active genes have low methylation levels. During development, methylation levels are changed, so the same gene may have different patterns of methylation (marks) in different tissues. These alternative patterns can be transmitted to daughter cells. They are transmitted because methylation occurs symmetrically, usually in CG doublets (or in plants in CNG triplets, where N can be any base) in which CmG on one strand is paired with GC"' on the other.
So, the correct answer is 'CmG'.
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