Question

Methylation of DNA most commonly occurs in which of the following sequence?

• A. $C_{p}G$
• B. $C_{p}A$
• C. $C_{p}T$
• D. $C_{p}C$

Answer 1

The correct option is A $C_{p}G$

DNA methylation takes place mostly in CpG rich sites. These sites are found in vicinity of certain genes. It includes methylation of cytosine into 5-methylcytosine that in turn alter the gene expression. Mostly, methylation suppress the gene expression. Correct option is A.