Question

Mitchell's chemiosmotic theory belongs to:

• A. Kreb's cycle
• B. Oxidative phosphorylation
• C. Glycolysis
• D. None of the above

Answer 1

The correct option is B Oxidative phosphorylation

Chemiosmotic theory describes ATP formation in mitochodria through oxidative phosphorylation. Electron transport chain includes downhill flow of electrons to final electron acceptor (Oxygen, which is then reduced into water) through a chain of membrane-bound carriers to facilitate the uphill transport of protons across a proton-impermeable membrane. Transfer of electrons through electron transport chain is accompanied by proton transfer across the membrane which in turn produces both a chemical gradient and an electrical gradient. Since inner mitochondrial membrane is impermeable to protons; protons can reenter the matrix only through Fo particles of ATP synthase. The proton-motive force that drives protons back into the matrix provides the energy for ATP synthesis. Correct answer is B.