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Question

Mode of DNA replication in E. coli is:

A
Conservative and unidirectional.
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B
Semiconservative and unidirectional.
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C
Conservative and bidirectional.
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D
Semiconservative and bidirectional.
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Solution

The correct option is D Semiconservative and bidirectional.
The region of replicating DNA associated with the single origin is called a replication bubble or replication eye and consists of two replication forks moving in opposite direction around the DNA circle. During DNA replication, the two parental strands separate and each acts as a template to direct the enzyme-catalyzed replication. So the mode of DNA replication in E.coli is semi-conservative and bidirectional.

Conservative replication would leave the two original template DNA strands together in a double helix and would produce a copy composed of two new strands containing all of the new DNA base pairs.

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