Molecules cannot penetrate or spread through cracks in between cells. This is due the presence of

Gap Junction

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Tight junction

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Desmosome

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Adherens junction

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Solution

The correct option is B
Tight junction

Tight Junctions: Occur in cells that are joined by collars of tightly fused membranes. Molecules cannot penetrate or spread through cracks in between cells.
Example includes Lining of the intestine (the only way molecules can get past is through controlled channels or carrier molecules in plasma membrane).

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