Question

Mongolism, Patau's syndrome and Edward's syndrome are due to

• A. Allosomal abnormalities
• B. Autosomal abnormalities
• C. Both A and B
• D. None of these

Answer 1

The correct option is B Autosomal abnormalities

1) Human disorders due to chromosome alterations in autosomes (sex chromosomes) are called autosomal abnormalities.

2) Autosomal Abnormalities: The majority of human chromosomal abnormalities occur in the autosomes. Most of these abnormalities are monosomies or trisomies.

3) People with Down syndrome (Mongolism) have an irregularity with autosome pair 21. In most cases, there is an extra chromosome (i.e., trisomy 21).

4) Edwards syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on the 18th chromosome, either in whole (trisomy 18) or in part.

5) Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13.

So, the correct answer is 'Autosomal abnormalities'.