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Question

Monoclonal antibodies are produced from hybrid cells called as hybridomas. The cells fused to obtain these hybridoma cells are

A
B-lymphocytes and myeloma cells
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B
Lymphoma cells and bone marrow cells
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C
T-lymphocytes and myeloma cells
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D
B-lymphocytes and carcinoma cells
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Solution

The correct option is A B-lymphocytes and myeloma cells
Hybridoma technology is a technology of formation of hybrid cell lines i.e., hybridomas by the fusion of B-lymphocyte cell and a myeloma cell. The hybrid cell produced is selected on the basis of its ability to grow in tissue culture and for an absence of antibody chain synthesis. The antibodies produced by the hybridoma cells are the single specific and therefore called as monoclonal antibodies.

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