Question

Monoclonal antibodies are produced from hybrid cells called hybridomas . The cells used to form hybridoma cells are

• A. T-lymphocytes and myeloma cells
• B. B-lymphocytes and carcinoma cells
• C. B-lymphocytes and myeloma cells
• D. Lymphoma cells and bone marrow cells

Answer 1

The correct option is C B-lymphocytes and myeloma cells

Hybridoma technology is a technology of formation of hybrid cell lines i.e., hybridomas by the fusion of B-lymphocyte cell and a myeloma cell. The hybrid cell produced is selected on the basis of its ability to grow in tissue culture and for an absence of antibody chain synthesis. The antibodies produced by the hybridoma cells are the single specific and therefore called as monoclonal antibodies.
So, the correct option is C.