Morphine is an important analgesic.
What interactions are involved in binding the phenol group to the target binding site?

Ionic interactions

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Hydrogen bonding interactions

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Van der Waals binding interactions

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The group has no binding role

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Solution

The correct option is B Hydrogen bonding interactions
The Phenol group is capable of acting as a hydrogen bond donor or a hydrogen bond acceptor. Analogous lacking phenol group have significantly lower activity.

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What type of forces are involved in binding of substrate to the active site of enzyme?

Regarding assertion and reason, choose the correct option.

Assertion [A]: Partial pressure of oxygen is an important factor affecting binding.

Reason [R]: The binding of oxygen with haemoglobin is primarily related to partial pressure.

E_{1}

α

E_{2}

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