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Question

Mr. Christoper is color blind and carrier for PKU. What percentages of sperms possesses defective allele for both?

A
0%
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B
25%
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C
50%
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D
100%
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Solution

The correct option is B 25%
  • In humans, the allele for colorblindness is present on the X chromosome.
  • In contrast, PKU (Phenylketonuria) shows autosomal inheritance as the alleles for the gene are present on chromosome number 12.
As Mr. Christopher is a carrier for PKU, he must carry only one defective allele. Thus, the probability of sperm to carry the defective allele would be 1/2 or 0.5.
  • Now, we know that the probability of sperm to carry X chromosome (defective allele for colorblindness) is 0.5
Thus, the probability of a sperm carrying the defective alleles for both the disorder would be = 0.5 x 0.5 = 0.025 i.e 25%.

  • So, the correct answer is '25%'.

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