The correct option is A Darkening of skin in lower vertebrates
Pars intermedia or middle lobe of pituitary is the boundary between the anterior and posterior lobes of the pituitary. It contains three types of cells – basophils, chromophobes and colloid – filled cysts. This area produces melanocyte stimulating hormone or MSH. It stimulates the synthesis of black pigment melanin in the skin and also causes dispersion of melanin granules in the pigment cells, thereby darkening the colour in certain animals (fishes; amphibians). In man it has no such role.