Muscular and nervous excitability is lowered by which of the following?

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Solution

The correct option is D K
High extracellular K+ leads to depolarization and ensuing inactivation of voltage-gated Na+ channels and loss of excitability in isolated muscles, exercise-induced loss of K+ is likely to reduce muscle excitability and thereby contribute to muscle fatigue. Hence, Muscular and nervous excitability is lowered by K.
So, the correct answer is 'K'.

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