The correct option is
B Hyposecretion of thyroid hormone
Myxoedema is also known as Gull's disease. It occurs commonly in adults due to hyposecretion of thyroid hormones after the normal physical and mental development of body is complete. The metabolic rate of body becomes low and oxygen consumption by metabolically active tissues gets decreased. Physical and mental processes of the body get slower, hair lose lustre and get brittle and skin becomes coarse.
So, the correct answer is 'Hyposecretion of thyroid hormone'.