Question

Name an instance where a transcription factor serves as its own repressor?

Answer 1

Transcription factors:

1. Transcription factors are the proteins involved in process of transcribing, DNA into RNA.
2. Transcription factors include a wide number of proteins, excluding RNA polymerase, which initiate and regulate the transcription of genes.
3. A defining feature of TFs is that they generally contain at least one DNA-binding domain (DBD), which attaches itself to a specific sequence of DNA adjacent to genes that they regulate.
4. In negative feedback loop mechanisms, the transcription factor acts as its own repressor also known as an inhibitory loop.
5. It is a type of self-regulating system.
6. In a negative feedback loop, increased output from the system inhibits future production by the system.
7. The body reduces the amount of certain proteins or hormones it creates when its levels get too high.
8. It happens when the original effect of the stimulus is reduced by the output.
9. The negative feedback mechanism normalizes functions when they become quite extreme.