Lysosomes are the membrane-bound organelles and area within their membrane is known as the lumen, which generally contains hydrolytic enzymes and other cellular debris.
The key function of the lysosomes is the digestion & removal of waste.
Cellular debris or any foreign particles are pulled inside the cell through the process of endocytosis.
A vacuole is also a membrane bound structure found in cytoplasmic matrix of a cell.
The membranes are composed of the phospholipids.
Vacuoles store the nutrients & water.
They also store waste from cell and prevents cell from the contamination.