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Question

Name the condition when the concentration of ketone body increases in urine.

A
Acromegaly
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B
Diabetes mellitus
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C
Diabetes insipidus
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D
Cushing's disease
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Solution

The correct option is A Diabetes mellitus
Acidosis is due to rapid fat catabolism. This leads to high levels of acetoacetic acid, which is converted to acetone and beta-hydroxybutyric acid. These three molecules known as ketone bodies. The presence of excreted ketone bodies in urine and in expired air is used as one diagnostic test for diabetes mellitus. Thus, the correct answer is option B.

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