1
Question
Name the ion responsible for masking active sites for myosin for cross-bridge activity during muscle contraction.
Name the ion responsible for masking active sites for myosin for cross-bridge activity during muscle contraction.
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Solution
The correct option is B Calcium
- Active sites for myosin(Thick filament) are present on actin which are masked by troponin in resting state. when Ca++ level increases it leads to the binding of calcium with a subunit of troponin on actin(thin) filaments and thereby remove the masking of active sites for myosin.
- Utilizing the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge.
- This pulls the attached actin filaments towards the centre of ‘A’ band.
- The ‘Z’ line attached to these actins are also pulled inwards thereby causing a shortening of the sarcomere, i.e., contraction.
- Hence the ion responsible for masking active sites for myosin for cross-bridge activity during muscle contraction is calcium.
- So, the correct answer is 'Calcium'
- Active sites for myosin(Thick filament) are present on actin which are masked by troponin in resting state. when Ca++ level increases it leads to the binding of calcium with a subunit of troponin on actin(thin) filaments and thereby remove the masking of active sites for myosin.
- Utilizing the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge.
- This pulls the attached actin filaments towards the centre of ‘A’ band.
- The ‘Z’ line attached to these actins are also pulled inwards thereby causing a shortening of the sarcomere, i.e., contraction.
- Hence the ion responsible for masking active sites for myosin for cross-bridge activity during muscle contraction is calcium.
- So, the correct answer is 'Calcium'
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