Question

Net gain of ATP from one molecule of glucose in glycolysis in aerobic organisms is

• A. 3
• B. 6
• C. 8
• D. 2

Answer 1

The correct option is C 8

In glycolysis, 2 molecules of ATP are consumed initially in converting glucose to fructose 1, 6-bisphosphate.
Four molecules of ATP are produced at substrate level phosphorylation, along with the generation of 2 molecules of $NAD{H}^{+}$. These $NAD{H}^{+}$ molecules are further utilized in the ETC to give rise to a total of 6 molecules of ATP (3 ATP per $NAD{H}^{+}$).
Therefore, the net gain of ATP in glycolysis in aerobic organisms is 8 ATP.