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Question

Net gain of glycolysis is

A
3 ATP and 1 NADH2
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B
2 ATP and 2 NADH2
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C
6 ATP and 4 NADH2
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D
10 ATP and 6 NADH2
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Solution

The correct option is B 2 ATP and 2 NADH2
Glycolysisis an oxygen independent metabolic process that converts glucose into pyruvate.
The steps invovled in glycolysis reaction is separated into two phases - The preparatory phase and the pay-off phase.
The first five steps of the glycolysis reaction is known as the preparatory phase. A total of 2 ATP molecules are consumed during the preparatory phase.
The remianing steps of glycolysis are known as the pay-off phase. This phase is characterized by gain of the energy-rich molecules ATP and NADH.
A total of 4 ATP and 2 NADH2 are obtained at the end of this phase of glycolysis.
Therefore at the end of glycolysis, a net sum of 2 ATP and 2 NADH2 molecules are obtained.

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